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Cardiovascular disease is the number one cause of death worldwide. Besides being highest cause of deaths in general, people living beyond the age of 80 most often die from some form of cardiovascular disease (including heart failure). Vascular Strength™ supports healthy vascular function. One of the key ingredients in this superior formula is from Bergamot (Citrus Bergamia Risso), a citrus plant that grows almost exclusively in the narrow coastal Calabria region in Southern Italy. The branded form of Bergamont used the vascular formula is Bergamonte®. Bergamonte® contains bioactive compounds of extract of the juice and albedo of citrus bergamia risso, standardized to > 30% polyphenolic flavanoids consisting of Naringin, Neohesperidin, Neoeriocitrin, 1% Melitidine, and 2% Brutelidine. Bergamonte® is produced using patented extraction technology through collaborative works of various Universities and research institutions in Italy.
IMPROVES TRIGLYCERIDE-HDL RATIO: High triglyceride-HDL ratios have a strong correlation with negative cardiovascular outcomes. Furthermore, higher ratios are also predictive of insulin resistance and diabetes. Vascular Strength™ may support significant improvement in reducing triglycerides and increasing HDL.
ACTIVATES AMPK (AMP-activated protein kinase) : AMPK is associated with longevity, and has been shown to extend the lifespan of lab animals. Furthermore, AMPK promotes health glucose and lipid levels, as well as mitigating cardiac fibrosis development. Fibrosis of the myocardium (heart muscle) reduces the function of the heart and is responsible for considerable mortality and morbidity. (Daskalopoulos EP, et al, J Mol. Cell Cardiol, 2016)
PREVENTION OF NON-ALCOHOLIC FATTY LIVER (NAFL). The liver is a key regulator of blood sugar in the blood stream. Excess sugar in the blood is taken in by the liver and converted to fat. This fat is then released back into the blood as triglycerides. However, when excessive fat accumulates in the liver, the liver loses the ability as a key regulator of blood glucose levels. This condition is known as Non-Alcoholic Fatty Liver (NAFL). NAFL is the most common liver disease in the industrialized world. Since NAFL leads to increased blood sugar it is strongly correlated to cardiovascular disease and diabetes. Bergamot polyphenols may prevent NAFL disease, and maintain the critical functioning of the liver, by inducing increased lipophagy (lipid metabolism) in the liver. (Parafati M, et al, J Nutr. Biochem, 2015)
Furthermore cardiovascular health is a function of not only cholesterol but also chronic inflammation of the blood vessels. Chronic inflammation in the blood vessel walls disrupts the normal lining of the blood vessels (endothelium) and triggers a cascade of events leading to atherosclerosis. In fact, inflammation is such an important factor in the development of cardiovascular disease, that 50% of people experiencing heart attacks had been previously diagnosed as having normal cholesterol. Vascular Strength™ provides a dual action support for cardiovascular health (1) Healthy cholesterol and triglycerides and (2) Healthy inflammatory response for blood vessels.
Ingredient Research for Vascular Strength.
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