Diabetes is a age accelerating disease, which affects every part of the body. High blood sugar, indicative of pre-diabetes, in addition to full diabetes, has become very common in an age of obesity, poor diet and insufficient exercise, in most of the modern world. Excessive blood sugar damages the brain, eyes, cardiovascular system, and every cell in the body. Important target areas include: AGEs (and precursor Methylglyoxal) and preservation of vascular regulating pericytes. Oxidative stress in the development of Diabetes and resulting complications.