WELCOME TO GERES DENGLE!

Thank you for visiting our site. We offer select nutrition supplement products from the finest sources world wide. Our finished products provide what you would expect from a quality supplement, including exceptional value. We hope you enjoy your visit to our site!

FREE SHIPPING on orders of $80 or more (for standard shipping in USA).

News

Prolongevity: New Evidence of Anti-Aging Effect of Resveratrol

July 25, 2021

For years, it has been known that resveratrol is one of the most effective anti-aging compounds studied. Beneficial effects on lifespan have been demonstrated across many research organisms, including worms and flies. In 2003, resveratrol was identified as a molecule which could activate SIRT1, mimicking the life extending benefits shown by calorie restriction. Furthermore, resveratrol also activates the anti-aging Nrf2 pathway, and AMPK which enhances NAD+ availability. (1) Cellular NAD+ levels are linked to longevity.  In a new study, the silkworm was used to further illustrate the life extending effects of resveratrol via significant improvement of antioxidant activity.. Oxidation is a key factor is anti-aging and shortening of the lifespan.(2) Resveratrol was shown to activate antioxidant function in the silkworm via increased activity...

Continue Reading →

PURPLE LONGEVITY® - Rich purple Anthocyanins, Activating Longevity Genes Autophagy and Increasing Glutathione

April 10, 2021

Boosting longevity is a function of many different attributes. Key among these are activating longevity genes (SIRT1 and FOXO) and decreasing levels of oxidative stress.  ACTIVATING LONGEVITY GENES - Resveratrol and Pterostilbene  - Act as antiaging gene activators, including SIRT1 gene activator.(1) Resveratrol and Pterostilbene are correlated with longevity. Lingonberry (Lowbush Cranberry) contains powerful anthocyanins which activate FOXO longevity genes. (2) Lingonberry may have beneficial effects on obesity health issues, including high fat diet cholesterol, glucose and inflammation.(3) BILBERRY ANTHOCYANINS (Blue Color) Significant increases antioxidant capacity and induction of autophagy (4) AUTOPHAGY promotes health and longevity. AUTOPHAGY - invoked through increased AMPK and reduced mTOR AUTOPHAGY further enhanced intestinal epithelial barrier  GRAPE SEED EXTRACT (GSE) (5-8) GSE grape seeds are anti-oxidative, anti-inflammatory...

Continue Reading →

Lycium Barbarum - for Vision (Retina) | Longevity | Intestinal Health and Slows Aging!

February 07, 2021

Lycium Barbarum (LB), also known as wolfberry, has been shown to provide powerful anti-aging effects. Significantly, long term feeding of LB in lab animals have shown increased longevity, eye (retina) support, including age-related macular degeneration (AMD), support liver health and boost of intestinal health and immunity.(1)     INCREASING MEAN LIFESPAN Studies involving D. melanogaster (fruit fly), shown LB increases serum and organ levels of superoxide dismutase (SOD), reduced glutathione and catalase (CAT) antioxidant activity. SOD and CAT have been shown in research models to promote longevity. (2) Positively promotes anti-aging pathways (MAPK, TOR, S6K) and increases expression of longevity genes (2) PRESERVING RETINA FUNCTION Retinal diseases have underlying high levels of oxidative stress. Photoreceptors and RPE (Retinal Pigment Endothelium) have very high metabolic activity and additional stress...

Continue Reading →

CURCUMIN PXC® - The Proteostasis Curcumin® and Fisetin for Longevity

January 02, 2021

PROTEOSTASIS. Defines the ability of the body to maintain the fidelity of  biogenesis of protein (non-defective proteins), folding. movement, and removal of old protein aggregates. Especially significant is the removal of old damaged protein aggregates, which are detrimental to the functioning of the cell. Clearing old cellular debris, through a process called autophagy, greatly enhances the youthful functioning of the cell.  CURCUMIN ENHANCES AUTOPHAGY. Lifespan and autophagy are strongly associated with one another.  Calorie restriction, resveratrol and curcumin are known to improve autophagy and increase lifespan. In fact, all life extension mechanisms depend upon the importance of autophagy for clearing cellular damage.(1,2) Aging affects molecular pathways that influence health and longevity. As a result, there is a reduction of cellular debris clearance (autophagy), decreased  the pool of...

Continue Reading →