The most visible effect of aging is the breakdown of the collagen rich connective tissue matrix which provides support for the skin. Sulfur, in the form of MSM (methylsulfonylmethane) maintains disulfide bonds that hold collagen strands in strong form and preserve the pliancy of connective tissue. By maintaining healthy collagen, cross-linking or "hardening" of the tissue is inhibited allowing for healthy dermal functioning as well as connective tissue forming the structural basis of the body.(1)
MSM supports longevity of the joint by strengthening connective tissue associated with cartilage, tendons and ligaments. Studies indicate that MSM helps prevent the degeneration of cartilage in the knee, while maintaining the strength of the tendons and ligaments.(2)
Since connective tissue is pivotal for the internal support of organs and blood vessels, MSM can also help maintain the internal support connective tissues.
Further benefits of MSM include increasing plasma levels of glutathione, anti-inflammatory and having a positive effect on autoimmune diseases.
Products with OptiMSM®: LONGEVITY NATURALLY™ CARTILAGE MAX™
REFERENCES:
(1) Bergstrom® Nutrition OptiMSM® information on the benefits of MSM. 2015.
(2) Ezaki J, et al.Assessment of safety and efficacy of methylsulfonylmethane on bone and knee joints in osteoarthritis animal model. J Bone Miner Metab, 2013 Jan,
Quality living meaning enjoying life. Perhaps the most important aspect is the sense of well being. Changes within our body, including increased inflammation in the brain, insulin resistance and stress, especially with aging, can affect the way we perceive ourselves and the world around us. For example, stress related pathways are implicated in depression. The stress response involves an increase in Cortisol (the stress hormone), and inflammatory cytokines which promotes insulin resistance.(1) Furthermore, the stress response is seen as a primary factor in metabolic syndrome. Chronically high cortisol levels is damaging to the body, which accelerates aging. Cortisol especially damages the health of the brain.(2,3)
Many natural gold and yellow ingredients support a healthy cortisol response (by acting as an adoptogen) and also promote reductions in inflammation in the brain and elevate GABA (feel good) neurotransmitters.(4-9)
Mental Well being support IMMORTALITY GOLD™ SERIES.
REFERENCES:
1. Gold, Phillip, et al. Clinical and Biochemical Manifestations of Depression: Relation to the Neurobiology of Stress. 2015 Mar 24.
2. Abdanipour A, et al. In vitro study of the long-term cortisol treatment effects on the growth rate and proliferation of the neural stem/precursor cells. Neurol Res. 2015 Feb.
3. Martocchia A, et al. Recent advances in the role of cortisol and metabolic syndrome in age-related degenerative diseases. Aging Clin Exp Res. 2015 Mar 27.
4. Panossian AG. Adaptogens in mental and behavioral disorders. Psychiatr Clin North Am. 2013 Mar.
5. Li J, et al. Effect of Schisandra chinensis on interleukins, glucose metabolism, and pituitary-adrenal and gonadal axis in rats under strenuous swimming exercise. Chin J Integr Med. 2015 Jan.
6. Zhao X, et al. Chronic curcumin treatment normalizes depression-like behaviors in mice with mononeuropathy: involvement of supraspinal serotonergic system and GABAA receptor. Psychopharmacology (Berl). 2014 May.
7. Bhatia N, et al. Adaptogenic potential of curcumin in experimental chronic stress and chronic unpredictable stress-induced memory deficits and alterations in functional homeostasis. J Nat Med. 2011 July.
8. Thakur AK, et al. Protective effects of Andrographis paniculata extract and pure andrographolide against chronic stress-triggered pathologies in rats. Cell Mol Neurobiol. 2014 Nov.
9. De la Pena JB, et al. Luteolin mediates the antidepressant-like effects of Cirsium japonicum in mice, possibly through modulation of the GABAA receptor. Arch Pharm Res. 2014 Feb.
As the world becomes more mobile, electronic devices have become essential in everyday life. However, the LED (Light Emitting Diode) screens of devices, including smartphones, computer screens, tablets and televisions, emit very high levels of blue light. The problem: blue light is very destructive to the retina of the eye, and may contribute to the development of AMD (Age-Related Macular Degeneration). In comparison, blue light produces 100 times more light induced retinal damage versus orange light. Higher levels of lutein and zeaxanthin in the retina, which are very effective in absorbing toxic blue light, can help block this damage. Furthermore, the higher the macular density of these carotenoids the more effective the protection. VISION VITALITY™ contains high levels of lutein (35 mg) and zeaxanthin which promotes significant protection of the retina.
REFERENCES:
1. Kuse, Y, et al. .Damage of photoreceptor-derived cells in culture induced by light emitting diode-derived blue light. Sci Rep. 2014 Jun 9
2. Chamorro E, et al. Effects of light-emitting diode radiations on human retinal pigment epithelial cells in vitro. Photochem Photobiol. 2013 Mar-Apr.
3. Keyvan Koushan, et al. The role of Lutein in Eye-Related Disease. Nutrients. 2013
There has been a longstanding awareness that amyloid plaques in the brain are a major causative factor in the development of cognitive problems, including Alzheimer's Disease. However, recent research indicates that another major contributing factor in cognition is vascular impairment in the brain.(1) Current research suggests links between heart disease and dementia.(2) In fact, damage to the small blood vessels in the brain may significantly increase risk of cognitive problems with aging.
In recognition of the vascular component, we now offer a new specially priced package for brain health and maintenance which addresses both areas of concern. The new product is called NEURO PERPETUAL™ and combines support for brain protection and healthy blood flow to the brain.
REFERENCES:
1. de la Torre, JC. Cardiovascular risk factors promote brain hypoperfusion leading to cognitive decline and dementia. Cardiovasc Psychiatry Neurol.2012.
2. Ferreira LK, Tamashiro-Duran JH, Squarzoni P, et al. The link between cardiovascular risk, Alzheimer’s disease, and mild cognitive impairment: support from recent functional neuroimaging studies. Rev Bras Psiquiatr. 2014 Jun 10.
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