Cardiovascular disease is a significant causative factor in mortality. Saffron has important anti-aging benefits including improvement of cardiovascular health. The bioactive constituents of saffron (Crocin and Crocetin) play major roles in cardiovascular fitness.
Significantly, saffron may therapeutically provide cardiovascular benefits in the following manner: (1)
Hypertension / Blood Pressure.- Studies indicate that saffron may lower diastolic blood pressure. Much of this involved relaxation of blood vessels. Further saffron may increase nitric oxide levels, which also promote lowering of blood pressure.
Inhibit LDL Cholesterol Oxidation - As a potent antioxidant, saffron has been shown to inhibit LDL oxidation. Oxidized LDL is a component of atherosclerotic plaques.
Inhibits Foam Cell Formation - Macrophage foam cell formation is a critical stage in the development of atherosclerosis. Active saffron components crocin and crocetin inhibit foam cells from developing.
Inhibits Vascular Cell Adhesion Molecule-1 (VCAM-1) - Another important factor in atherosclerosis development. Again, VCAM-1 is suppressed by crocin and crocetin.
VASCULAR VX™ (Includes Saffron with Crocin and Crocetin)
(1) Roshanravan N, et al. The therapeutic potential of Crocus sativus Linn.: A comprehensive narrative review of clinical trials. Phytother Res. 2022 Jan